Abstract
Perforating granuloma annulare (GA) is a rare subset of GA with an unknown etiology and chronic course. Herein, we report the case of 72 year-old women with a 3-month history of a post-traumatic, persistent, erythematous and exudative plaque located on her left leg. Differential diagnosis included mycobacterial infection, subcutaneous mycosis, perforating dermatoses, pyoderma and squamous cell carcinoma. The histopathology was highly suggestive of a perforating GA. The patient was treated with betamethasone dipropionate cream applied once daily and a complete resolution of the lesion was observed in three weeks. Despite being a very rare subtype of a common disease, perforating granuloma annulare has clinical and histopathological characteristic features that facilitate the differential diagnosis, avoiding unnecessary procedures and inadequate and potentially more invasive treatments.
Highlights
Perforating granuloma annulare (GA) is a rare subset of GA with an unknown etiology and chronic course [1]
Perforating granuloma annulare was first described by Owens and Freeman in 1971
It is a rare subset of GA with a chronic course and unknown etiology
Summary
Perforating granuloma annulare (GA) is a rare subset of GA with an unknown etiology and chronic course [1]. It occurs most frequently in childhood and it appears as umbilicated papules that involve, most commonly, the extremities [2]. The diagnosis is often difficult and challenging. Healthcare 2014, 2 and histopathological features that facilitate the differential diagnosis, avoiding unnecessary procedures or inadequate treatments
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