Abstract
Perfluorocarbon nanodroplets can be triggered to undergo a liquid-to-gas phase transition with an externally applied acoustic pulse. The resulting gaseous bubbles provide strong ultrasound contrast, enabling visualization of their distribution. This talk will focus on recent advances in imaging methods that enable multiplex and molecular imaging using the nanodroplets. In addition, a double-emulsion nanodroplet will be presented that simultaneously encapsulates hydrophobic and hydrophilic drugs. These dual-drug loaded nanodroplets can be used for on-demand delivery of combination chemotherapy and/or immunotherapy to a site of interest.
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