Abstract

Perfluorinated compoundc (PFCs) are synthetic chemicals that are persistent in the environment and bioaccumulate in humans and animals. These substances are ubiquitous in drinking water, cookware, stain repellents, food storage, packing materials, and cosmetics. Perfluorooctanoic acid (PFOA) is the most commonly detected PFC and has been associated with reduced fecundity and infertility. Ovarian gap junctions facilitate the transfer of various nutrients, ions, metabolites, and nucleotides between follicular cells and the oocyte.

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