Abstract
There is a paucity of data about optimal perinatal management of patients with May-Hegglin anomaly. Percutaneous umbilical blood sampling was used in two separate pregnancies in a patient with this disorder to determine if a trial of labor could be allowed. The second infant inherited the disease, although cordocentesis at term revealed a normal fetal platelet count. There were no hemostatic complications in either infant. Our review of the pediatric literature failed to identify fetal or neonatal traumatic hemorrhage in patients with May-Hegglin anomaly. Therefore, percutaneous umbilical blood sampling seems unwarranted in patients with this disorder.
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