Abstract
Objective To investigate the surgery outcomes between patients with different recovery states measured by visual analog scores (VAS), explore the relationships among surgery outcomes, bone cement, and degrees of pain relief, and to find out the best combination of cement volume and cement distribution for Percutaneous kyphoplasty (PKP). Methods There were 220 patients with 220 vertebra, from January 2012 to January 2014, who received PKP in our hospital. Patients were divided into two groups, on the basis of different VAS. The epidemiological data, operative effect, and surgical complications were compared between two groups. Characteristic curve (ROC) was used to analyze the effect of bone cement dosage and distribution on the diagnosis of patients with different recovery state. The correlation was analyzed between the dose and distribution of bone cement and surgery outcomes. Moreover, logistic regression analysis was used to assess the safety of cement implantation. Results A total of 77 recuperators and 143 non-recuperators were included in the study. Two groups of patients in epidemiological data showed no significant difference. The surgery duration, bone cement injection dose, cement distribution, vertebral height restoration rate and improvement of kyphotic angle in the recuperator group were all significantly higher than those in the non-recuperator group. Whether small dose and large dose of bone cement volume and expanded the bone cement distribution area could significantly improve the patient of operation after the recovery rate and bone cement dose with extensive bone cement distribution area and large bone cement dose with limited bone cement distribution area had the same operation after the recovery effect (χ2=2.880, P=0.090). When the cement volume was constant, cement distribution was positively correlated with the restoration rate of vertebral height and improvement of the kyphotic angle (r2=0.207, P<0.01; r2=0.159, P=0.02). Conclusions The value of cement distribution is better than cement volume in relieving patient pain for diagnostic. For PKP, cement distribution above 0.49 with small cement should be suggested. Key words: Bone cements; Vertebroplasty; Pain measurement
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