Abstract
A critical factor in the evaluation of the risk associated with cutaneous exposure to chemical substances is an information relating to the percutaneous absorption of these substances. Recent developments in the percutaneous absorption of chemical substances in industry, especially organic solvents, are reviewed, and these percutaneous absorption rates in humans and animals exposed in vivo and their excised skin in vitro from vapor and liquid phase are summarized. Evaluations concerning the amounts of percutaneous absorption in vivo of organic solvents in toxicity are discussed by a mathematical model by using the percutaneous absorption coefficient for vapor phase and the percutaneous absorption rate for liquid phase, and recommendations for future research of organic solvents are proposed from the relationship between these chemical-physical properties and these percutaneous absorption rates.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
