Abstract
According to National Sleep Foundation in America, more than one third (36%) in young adults aged 18-29 years old reported hard to wake up in the morning. Nutmeg seeds contain atsiri oil about 10% and miristin that have sedative effect. The purpose of this study is to prove that nutmeg seeds shorten sleep induction time and prolong sleep time. This type of research is experimental research with a post test only control group design. The samples used were 27 male Swiss Webster mice, which were divided into three groups. The first control group was given diazepam; the second group was given nutmeg seed extract dose of 7.5 mg; and the third group was given aquabides. The data obtained from the sleep duration of mice in each group. To determine differences in each experimental group, data with normal distribution were analyzed by one way ANOVA test and data with abnormal distribution were analyzed by the KruskalWallis test using SPSS 22.0 for Windows. The results of the Kruskal-Wallis test showed that sleep induction time had a value of p = 0.001. Based on the one way ANOVA test, the result shows the length of sleep time from the treatment group has a significant difference to the control group with a value of p = 0,000 and also showing a significant result to the comparison group with a value of p = 0,000. Nutmeg seed extract (Myristica fragrans Houtt.) with a dose of 7.5 mg can significantly extend the sleep duration of mice. Keywords: nutmeg seeds extract, sleep duration.
Highlights
Tidak memandang status kaya, miskin, yang sangat penting, karena tidur dapat pendidikan rendah maupun tinggi.[1] mengendalikan irama kehidupan
The purpose of this study is to prove that nutmeg seeds shorten sleep induction time and prolong sleep time
Pulmonologi Ilmu Kedokt oleh Winarti dan Nurdjanah padaZhurnal Eksp i Teor pinen, sabinen, kamfen, miristicin, Fiz. 2011:68
Summary
Miskin, yang sangat penting, karena tidur dapat pendidikan rendah maupun tinggi.[1] mengendalikan irama kehidupan. Tahun 2004 dari 238,452 sepertiga dari kehidupannya untuk juta penduduk sebanyak 28,053 juta tidur. Hal setiap manusia pernah mengalami ini diperkuat dengan hasil survei masalah susah tidur. Beberapa masalah terbaru bahwa prevalensi insomnia di susah tidur dapat diatasi oleh individu. Terlebih diagnosis diri (self diagnose) menjadi sangat penting.[1] lagi National Sleep Foundation menyatakan bahwa di Indonesia. Fungsi tidur adalah restorative prevalensi penderita insomnia (memperbaiki) kembali organ – organ mencapai 70% paling sedikit seminggu tubuh. Kegiatan memperbaiki kembali sekali dan 30 juta orang sulit tidur tersebut berbeda saat Rapid Eye setiap malamnya 2
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