Perbandingan Gambaran Foto Toraks Pasien TB-HIV Dua dan Enam Bulan Pengobatan Anti-Tuberkulosis + Anti-Retroviral

Abstract

Background: Tuberculosis (TB) remains a global health issues and mostly located in developing countries. As cases of HIV/AIDS increase every year, it is estimated that TB cases also increase. TB is the leading cause of death in people with HIV and HIV infection, and became the biggest risk factor in the conversion of latent TB cases to become active TB. Radiographic manifestation of TB in AIDS patients depends on antiretroviral therapy (ART).Materials and Methods: This is an observational study which compares 2 and 6 months chest radiographs from TB-HIV patients with anti-TB drugs+ART in 24 adults patients with TB-HIV in the Internal Medicine Polyclinic and Ward at Dr. Kariadi Hospital and BKPM Semarang.Result: Most patients were male with 19 subjects (79.2%). The large stage group based on the proportion of AIDS cases is 20-29 years (45.84%). After 6 months of anti-TB drugs+ART there were radiographic improvement in consolidation, cavitation, lymphadenopathy and pleural e?usion. Wilcoxon Signed Ranks Test showed signifcant changes in consolidation and lymphadenopathy between 2 and 6 months of anti-TB drugs+ART, but no signifcant changes in cavity and pleural e?usion.Discussion: At 6 months chest radiographs examination, not all patients with anti-TB drugs+ART show radiographic improvement. Therefore, the decision to stop TB therapy in HIV patients in 6 months time seems inadequate.Conclusion: There are signifcant change between 2 and 6 months of anti-TB drugs+ART with radiographic improvement are consolidation and lymphadenopathy.