Peptides that non-covalently functionalize single-walled carbon nanotubes to give controlled solubility characteristics

Abstract

Methods which solubilize single-walled carbon nanotubes (SWNTs) in water as individuals, not bundles, while retaining their unique electronic, photonic and mechanical properties are highly desirable. Furthermore, functionalization with a diverse array of selectable chemical moieties would allow the range of useful applications to be significantly extended and may permit the designed assembly of SWNT networks. This paper presents a series of peptides that non-covalently solubilize carbon nanotubes in water using a design motif that combines a combinatorial library sequence to bind to nanotubes with a rationally designed section to create environmentally tuned solubility characteristics. The ability of the peptides to individually disperse carbon nanotubes without altering their electronic structure is shown by vis-NIR absorbance, fluorescence, and regular and vitreous ice cryo-TEM. Identification of the species composition of each sample by NIR fluorescence reveals that the peptides exhibit some diameter selectivity. Additionally, one of the rationally designed modifications addresses the poor stability of non-covalently solubilized SWNT suspensions by including cysteine residues for covalent crosslinking between adjacent peptides.