Abstract
This is a prospective comparison between heater probes and hemoclips for peptic ulcer-related bleeding. One hundred thirteen patients with bleeding ulcers and major stigmata of hemorrhage were randomized to receive either stainless steel hemoclips or heater probe treatment. An average of three clips were used in each patient. Endoscopic therapy failed in eight patients in the heater probe group and six in the hemoclip group. Recurrent bleeding occurred in 21% of patients treated with the heater probe and 1.8% treated with the hemoclips ( p < 0.05). No major procedure-related complications occurred. Hemostasis rates, adequate treatment of the visible vessel, 30-day mortality, and emergency surgery rates were similar in both groups. The relative risk reduction for recurrent bleeding with the hemoclip was 91%, with a number needed to treat of 6.
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