Abstract
Introduction. Flavonoidal class chemical have numerous medicinal importance and pharmacological activities. Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) enzymes play an important role in various forms of neurodegenerative disorders. Pectolinarin is an important flavonoid found to be present in the Cirsium japonicum. Methods. In order to understand the beneficial health aspect of flavonoids in neurodegenerative disorders, present work summarized the health beneficial properties of Pectolinarin through literature data analysis of various scientific research works. Neuroprotective effects of Pectolinarin in the management of neurodegenerative disorders ‘Alzheimer's disease’ have been presented here in this study. Different biological experiments have been conducted in the scientific field and data were collected from different literature database to explore the neuroprotective potential of Pectolinarin in the medicine. Role of antioxidant in the Alzheimer's disease have been also investigated and analyzed through literature data analysis of various research work and presented in this investigation. Importance of AChE and BuChE in the neurodegenerative disorders have been also investigated through literature data analysis of different research work. Results. Literature data analysis of various scientific research works revealed the beneficial effects of pectolinarin in the medicine for the treatment of neurodegenerative disorders. Scientific data analysis of various literatures revealed the biological importance of pectolinarin against oxidative stress and cell death induced by H2O2. Literature data analysis of research work revealed the antidepressant activity of pectolinarin in various animal models. Molecular study data analysis revealed the biological importance of AChE and BuChE in the treatment of neurodegenerative disorders and highlighted the key role of pectolinarin in the medicine for the development of newer medicine against various forms of neurodegenerative disorders. Conclusion. Literature data analysis of different research works revealed the biological potential of pectolinarin in neurodegenerative disorders which could be beneficial for the treatment of Alzheimer's disease in the future.
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