Abstract
The title compound, C22H25F5N4O9, is a stable pentafluorophenyl ester intermediate in the synthesis of novel homo-oligomeric structures containing branched carbon chains. The structure is epimeric to the previously characterized dimeric pentafluorophenyl ester with stereochemistry (3R,4R,5R), which was synthesized using d-ribose as starting material. The crystal structure of the title molecule removes any ambiguities arising from the relative stereochemistries of the six chiral centres. Two hydrogen bonds, bifurcating from the NH group, stabilize the crystal: one intramolecular and one intermolecular, both involving O atoms of the methoxy groups. The asymmetric unit contains two independent molecules not related by any pseudo-symmetry operators. The major conformational differences are localized, leading to one molecule being extended compared to the other. The collected crystal was twinned (twin ratio is 0.939:0.061), and the azide group is positionally disordered over two positions in one molecule [occupancy ratio 0.511 (18):0.489 (18)].
Highlights
The title compound, C22H25F5N4O9, is a stable pentafluorophenyl ester intermediate in the synthesis of novel homooligomeric structures containing branched carbon chains
For structures related to the title molecule, and their characteristic features, see: Punzo et al (2006); Humphreys et al (2005)
The crystal structure of the title molecule removes any ambiguities arising from the relative stereochemistries of the six chiral centres
Summary
Cowley et al (2004); Mayes, Simon et al (2004). For other procedures for the synthesis of branched sugars, see: Ho &. For the synthesis of the title compound, see: Simone et al (2008, 2010). For structures related to the title molecule, and their characteristic features, see: Punzo et al (2006); Humphreys et al (2005)
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