Peningkatan Kadar Kolesterol Darah Tikus Putih yang Diberikan Pakan Imbuhan Ragi Tape

Abstract

Tape yeast can be used as a source of genuine probiotics because tape yeast contain microbes such as molds, yeasts, and bacteria that are able to hydrolyze carbohydrates into glucose that are converted into alcohol. This study aimed to determine the effect of giving tape yeast for 21 days to the blood cholesterol levels of white rats(Rattus norvegicus). White rats were grouped into four treatments, namely P0: control; P1: under 100 mg/kg BW dose; P2: 200 mg/kg BW; and P3: 300 mg/kg BW of Tape yeast. The examination of blood cholesterol levels was tested by using EasyTouch GCU (Glucose, Cholesterol, and Uric Acid) with blue strips and chip tests. Blood samples were taken by cutting off tip of the tail and put the blood to the strip to see the results on the measuring device. The data obtained were analyzed by variancetest and data that were significantly different between treatments were continued with the Least Significance Different(LSD) test. The results of this study showed the average blood cholesterol level of treatment P1: 211.00 mg/dL, P2: 282.00 mg/dL and P3: 174.17 mg/dL higher than the control group P0: 149.67 mg/dL. Based on statistical tests were shown significantly different results on the treatment of P1 (100 mg/kg body weight), P2 (200 mg/kg body weight), and P3 (300 mg/kg body weight). Based on the result itcan be concluded the administration of tape yeast affects the blood cholesterol levels of white rats.