Abstract
There is a known link between erectile dysfunction (ED) and major depressive disorder (MDD). Previous studies have shown that pharmacologic management of ED is effective in reducing depressive symptoms. What is not known is whether placement of penile prosthesis may improve depressive symptoms in men with ED. We investigated whether penile prosthesis is protective against MDD in men with ED by querying a large, multicenter, electronic health record network (TriNetX), which contains data on roughly 60 hospitals and 66 million patients in the United States.
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