Abstract
IntroductionExtraskeletal osteosarcoma arising in the penis is exceedingly rare and its major differential diagnosis is sarcomatoid carcinoma.Case presentationA 19-year-old patient noticed a deep nodule in the dorsal side of the penis 2 years before this presentation. No skin lesions were noted until recent ulceration. In both biopsy and penectomy specimen, atypical mononuclear cells were diffusely positive for SATB2 (a marker of osteoblastic differentiation), CD99 and vimentin. These cells were negative for pan-keratin, SOX10, S100, EMA, GATA3 and CD68 was expressed only in multinucleated giant (osteoclast-like) cells. Few areas suggestive of osteoid production were noted.ConclusionIn high-grade sarcomas, including in the penis, SATB2 staining may be useful to identify extraskeletal osteosarcoma.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
