Abstract
A case of penile gangrene caused by secondary hyperparathyoidism from chronic renal failure is presented. Total penectomy was used to control the septic condition. This case prompted a review of the literatures concerning secondary hyperparathyroidism in chronic renal failure which can lead to widespread ischemic necrosis and gangrene. In the early phase of uremia, careful monitoring of serum phosphate and calcium level may effectively prevent the development of secondary hyperparathyroidism. Once progressive calcification in the arterial wall and soft tissue has developed and the serum Ca × P product ＞75 mg/dl, subtotal parathyroidectomy is indicated.
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