Abstract
Penicillin inhibits the growth of bacteria; some authorities maintain that it is an extremely powerful bactericidal agent also. It is nontoxic in various amounts necessary for therapeutic purposes. This report is a continuation and combination of two previous preliminary reports published by Drs. Mahoney, Van Slyke and Arnold at the U. S. Marine Hospital, Staten Island, N. Y. This report is not made to establish the efficacy of penicillin in the treatment of gonorrhea but to try to determine the proper and minimal dosage to obtain the necessary cure. Numerous articles have appeared on treatment with penicillin. In the first one, by Herrell, Cook and Thompson,15 cases were reported in which the continuous intravenous drip method was employed with favorable results. In the second and third articles, byDr. Mahoney and his associates2and by Van Slyke, Arnold and Buchholtz,3the intramuscular route was employed. The
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