Abstract

Three types of semiconductor field-effect penicillin sensors, enzyme field-effect transistors (EnFETs), capacitive electrolyte–insulator–semiconductor (EIS) sensors and light-addressable potentiometric sensors (LAPS) have been developed and tested for the penicillin detection. For all sensor types the enzyme penicillinase was adsorptively immobilised directly onto a pH-sensitive Ta 2O 5 surface. Some basic parameters of these sensors (e.g. sensitivity, linear range, detection limit, response time, hysteresis and life time) are investigated and their performances with regard to the respective measurement set-up as well as the sensor configuration are compared.

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