Abstract

Results Total of 124 patients were evaluated for penicillin allergy. Mean age was 37.8 (SD 12.7) years, range from 8 to 74 years. 39 (31.5%) male and 85 (68.5%) female patients were included. Diagnosis of penicillin allergy was confirmed in 46 patients (37.1%). Among the 44 confirmed allergic patients by skin evaluation we had 15 (34.1%) positive skin prick test, and 29 (65.9%) positive intradermal testing. Among patients with positive skin testing, 47.7% were positive to PPL, 20.4% to MDM, 50.0% to PG and 40.9% to ampicillin; 13.6% of patients were positive to amoxicillin by skin prick test. One patient had positive RAST and one had a positive challenge test.

Highlights

  • Hypersensitivity to penicillin has been studied worldwide, but data regarding patterns of sensitization in Arabian Gulf countries are scarce.Authors’ details 1Allergy Center, Kuwait. 2Al-Rashed Allergy Center, Allergy Department, Kuwait.Published: 18 July 2014

  • 124 patients referred to the drug allergy clinic for penicillin allergy were fully evaluated by skin prick and intradermal testing

  • Total of 124 patients were evaluated for penicillin allergy

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Summary

Introduction

Hypersensitivity to penicillin has been studied worldwide, but data regarding patterns of sensitization in Arabian Gulf countries are scarce.Authors’ details 1Allergy Center, Kuwait. 2Al-Rashed Allergy Center, Allergy Department, Kuwait.Published: 18 July 2014. From 6th Drug Hypersensitivity Meeting (DHM 6) Bern, Switzerland. Background Hypersensitivity to penicillin has been studied worldwide, but data regarding patterns of sensitization in Arabian Gulf countries are scarce. Objectives To describe the patterns of penicillin hypersensitivity during a 6-years study in Kuwait in terms of demographics, type of the culprit drug, in-vivo and in-vitro allergy testing.

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