Abstract
Rationale Penicillin and other beta-lactams are the most commonly used antibiotics due to their narrow spectrum of activity, low cost and safety profile. However, an “allergy” to Penicillin is also the most commonly reported allergy. Approximately, 5-10% of all patients self-report an allergy to Penicillin and of these 99%) of skin testing to rule out true IgE mediated Penicillin allergy. Less than 10% of patients with a history of penicillin allergy are found to be actually allergic to penicillin on skin testing. Despite this, most physicians forgo further investigations in favor of the usage of alternative antibiotics.
Highlights
Rationale Penicillin and other beta-lactams are the most commonly used antibiotics due to their narrow spectrum of activity, low cost and safety profile
Less than 10% of patients with a history of penicillin allergy are found to be allergic to penicillin on skin testing
A questionnaire was designed to evaluate the referral practices of Anesthesiologists for a presumed Penicillin allergy
Summary
From Canadian Society of Allergy and Clinical Immunology Annual Scientific Meeting 2014 Ottawa, ON, Canada. 23-26 October 2014. From Canadian Society of Allergy and Clinical Immunology Annual Scientific Meeting 2014 Ottawa, ON, Canada. Rationale Penicillin and other beta-lactams are the most commonly used antibiotics due to their narrow spectrum of activity, low cost and safety profile. An “allergy” to Penicillin is the most commonly reported allergy. 5-10% of all patients self-report an allergy to Penicillin and of these 99%) of skin testing to rule out true IgE mediated Penicillin allergy. Less than 10% of patients with a history of penicillin allergy are found to be allergic to penicillin on skin testing. Most physicians forgo further investigations in favor of the usage of alternative antibiotics
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