Abstract
Summary Penicillamine is a heavy metal chelator which is used in the treatment of Wilson's disease, cystinuria, rheumatoid arthritis and scleroderma. The cutaneous side-effects of prolonged, high dose (1–2 g/day) treatment include skin fragility, elastosis perforans serpiginosa (EPS), cutis laxa and rarely pseudoxanthoma elasticum-like changes.1,2 We describe the clinical and post-mortem findings in a patient who developed pseudo-pseudoxanthoma elasticum and multi-system penicillamine-induced elastosis while taking D-penicillamine (750 mg/day). There are no previous reports of penicillamine-induced elastic tissue damage in a patient with rheumatoid arthritis.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
