Pengendalian Kimia dan Resistensi Vektor Anopheles Dewasa pada Kawasan Endemis Malaria di Dunia

Abstract

Background: Various methods of malaria vector control has been done. Insecticides which using repeatedly impact new problems for the emergence of vector resistance. Hence, optimization about active ingredient in the insecticide product should take notice to the development of insecticide resistance mechanisms for malaria vectors. Literature review which assess and discuss Anopheles sp resistance for chemical control programme were still limited to certain insecticides. The aim of this literature review is collecting and findings evidence has been produced by researchers which associated with chemical control of vector and variety of adult Anopheles resistance as a strategy to eradicate malaria endemic cases. Method: This literature review prepared by systematic review methods.Google database is used as the primary source of search with keyword adult Anopheles, resistance, insecticide”, and chemical control. Inclusion and exclusion criteria applied to select journals that are relevant of this literature review’s topic. Collected 41 articles and 10 articles are matched with inclusion criteria. Results: Chemical control obtain cause Anopheles sp resistance to certain chemical insecticides. The involvement of Anopheles sp knockdown resistance (kdr) mutations as a genetic factor in the resistance mechanism, bio-ecological factors and operational factors (insecticide types, application techniques, dose, frequency, time and manner of application/intervention) as the primary cause of chemical insecticide resistances. Conclusion: To maintain this programme, we needs government policies are vector control integrated through research, assessment, and development of vector resistance mechanisms with insecticides to achieve the goals for globally malaria’s free in 2020.