Abstract
Honey is a human food ingredient produced by bees. Honey is a special food ingredient and has high nutritional value, honey has been proven to be used as a burn medicine and as an antioxidant. More specifically and honey can be used to prevent liver damage due to obstruction of the common bile duct and due to cysticercus cysts in the liver. Honey is known to contain organic acids, minerals, vitamins, and is rich in active substances that act as antioxidants that can protect the liver from damage. Research also confirms that the phenolic antioxidants present in honey are very effective, thus increasing the body's resistance to fighting oxidative stress. Cigarette smoke contains 4000 types of organic substances and cigarette smoke can become free radicals that can cause oxidative stress and damage normal tissue. The method used in this study was true experimental with a post-test only controlled group design. Using 30 male mice, the results obtained were that the provision of honey had an effect on the microscopic image of the liver of male mice exposed to cigarette smoke, but the statistical test results did not show any significant differences between the control group and the treatment group. Further research is needed with different dose variations.
Highlights
Honey is a human food ingredient produced by bees
Using 30 male mice, the results obtained were that the provision of honey had an effect on the microscopic image of the liver of male mice exposed to cigarette smoke, but the statistical test results did not show any significant differences between the control group and the treatment group
Perbandingan Daya Hambat Madu Alami dengan Madu Kemasan secara In Vitro terhadap Streptococcus beta hemoliticus Group A sebagai Penyebab Faringitis.Jurnal Kesehatan Andalas,
Summary
Parameter yang digunakan pada sistem penilaian derajat kerusakan sel hepar adalah jumlah inti sel yang mengalami piknosis, karioreksis dan kariolisis. Pada Fotomikrograf kelompok perlakuan peneltian sebelumnya ,didapatkan hasil bahwa kandungan dalam madu tidak dapat memberikan efek protektif terhadap kerusakan struktur morfologi sel hepar mencit yang diberi paparan asap rokok (Oka Adi Parwata, Ratnayani, & Listya, 2010). Dari hasil uji One-way ANOVA, didapatkan perbedaan yang tidak bermakna dari nilai rata-rata jumlah kerusakan sel hepar mencit antara kelima kelompok. Kesimpulan yang didapatkan adalah ada perbedaan rata-rata skor kerusakan morfologi sel hepar yang tidak bermakna antara Kelompok Kontrol Normal, Kontrol Negatif, KP 1, KP 2, dan KP 3. Penelitian ini sejalan dengan penelitian yang dilakukan oleh Widigdo, 2014 yang menunjukkan hasil berupa flavonoid dapat memperbaiki kerusakan sel hepar dan asap rokok memiliki efek berupa merusak sel hepar.
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