Abstract
Avicel® PH is branded name from microcrystalline cellulose that is generally used in pharmaceutical preparations. Avicel® PH are being used as filler or binder in dosage formulas in tablets especially for direct compression because having a good flowing rate and a good compressibility. This study aims to compare the influence of the use Avicel® PH 101 and Avicel® PH 102 as a filler on of preparations a tablet of ascorbic acid. A method of the research was conducted by making granule of ascorbic acid tablet with the variation filler, then the granule was evaluate in .The results showed Avicel® PH 102 as a filler produce granule which better seen from the flowability, static angle of repose, carr’s index and hausner ratio .
Highlights
Avicel® PH is branded name from microcrystalline cellulose that is generally used in pharmaceutical preparations
Avicel® PH are being used as filler or binder in dosage formulas in tablets especially for direct compression because having a good flowing rate and a good compressibility
This study aims to compare the influence of the use Avicel® PH and Avicel® PH as a filler on of preparations a tablet of ascorbic acid
Summary
Avicel® PH is branded name from microcrystalline cellulose that is generally used in pharmaceutical preparations. PENGARUH BAHAN PENGISI TERHADAP MASSA CETAK TABLET VITAMIN C Avicel® PH banyak digunakan dalam pembuatan tablet secara kempa langsung karena memiliki laju alir dan kompresibilitas yang baik. Penelitian ini bertujuan untuk membandingkan pengaruh penggunaan Avicel® PH dan Avicel® PH sebagai bahan pengisi pada sediaan tablet vitamin C.
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