Pencitraan Kedokteran Nuklir Pada Pasien Metastasis Tulang dengan Kanker Payudara

Abstract

Bone is the most common site to which breast cancer metastasizes and sometimes is the first affected site in a substantial proportion of women with advanced breast cancer. A lot of study has highlighted that imaging modalities visualize different aspects of osseous tissues (cortex or marrow). Imaging bone metastases is problematic because the lesions can be osteolytic, osteoblastic, or mixed, and imaging modalities are based on either direct anatomic visualization of the bone or tumor or indirect measurements of bone or tumor metabolism. Bone imaging by skeletal scintigraphy can be an essential part, and positron emission tomography or single-photon emission computed tomography have a potential of evaluating bone metastases, but no consensus exists as to the best modality for diagnosing the lesion and for assessing its response to treatment. In this review, we discuss the use of each nuclear imaging for bone modality for diagnosing bone metastases from breast cancer