Abstract
Pemphigus vulgaris is an autoimmune disease characterized by the formation of vesicle-bullous lesions on the skin and mucous membranes. Such changes occur because of development of an autoimmune response directed to the desmosomes and epithelial tonofilaments. The aim of this study is to describe a case of erosive and ulcerative lesions in the region of marginal gingiva in a female patient, leucoderma, 34 years old, diagnosed after incisional biopsy of skin lesion and Nikolsky test. The patient has been followed-up for 2 years and during this period it was proposed as treatment of the buccal lesions the use of Gingilone® and dexamethasone mouth rinse, with satisfactory clinical result. Also, it was prescribed clobetasol propionate on individual tray in case of recurrent lesions. Currently, the patient is still under systemic treatment with azathioprine and prednisolone, presenting a significant improvement of mouth sores.
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