Abstract
Roselino et al. (2001) reported the first link between salivary proteins from sand flies and pemphigus foliaceus (PF) pathogenesis on the basis that patients living in a Brazilian region where PF is endemic showed higher titers of IgG antibodies against maxadilan, one of the most immunogenic salivary proteins described in Lutzomyia longipalpis, as compared to healthy controls (HC). For another Brazilian focus, Qian et al. (2012) reported that antibodies against LJM11, another highly immunogenic salivary protein from Lu. longipalpis, cross-react with Desmoglein (Dsg) 1.
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