Abstract
Cancer patients experience cancer-related fatigue (CRF) that are subjective and persistent. CRF can have a negative impact on psychosocial, spiritual, and self-perceived burden. To understand more deeply about CRF, we need to answer one fundamental question: how are the causal mechanisms (cause-effect) of the factors related to CRF. The studies related so far are still limited to correlation analysis between factors and have not focused on the mechanism of a causal relationship. The purpose of this study is to model the causal relationship between CRF and psychosocial, spiritual, and self-perceived burden, using a causal method called the Stable Specification Search for Cross-Sectional Data With Latent Variables (S3C-Latent). The results of this study are in the form of causal modeling between factors where self-burden has a causal relationship with CRF, spiritual need factors (religion) also have a causal relationship with CRF. Meanwhile, the social support factor (friends) with spiritual needs (religion) does not represent a causal relationship, but there is a strong association relationship. Meanwhile, the social support factor (friends) with CRF did not have a causal relationship or an association relationship between the two variables.
Highlights
Patients with cancer experience cancer-related fatigue (CRF) that can be subjective and persistent
The purpose of this study is to model the causal relationships between CRF, psychosocial, spiritual, and self-perceived burden (SPB), using a causal method called the Stable Specification Search for Cross-Sectional Data With Latent Variables (S3C-Latent)
The results show causal relationships from SPB to CRF with a reliability score of 0.67 and from spiritual need (religion) to CRF with reliability score 0.73
Summary
Kanker merupakan salah satu masalah utama kesehatan masyarakat di seluruh dunia [1]. Kanker adalah penyebab kematian terbesar kedua di seluruh dunia dan diperkirakan akan meningkat lebih dari 50% selama beberapa tahun mendatang [2]. Studi tersebut juga menemukan kanker melaporkan bahwa mereka mengalami kelelahan adanya korelasi negatif antara kedua variabel tersebut (p akibat depresi yang tinggi, nyeri, dan gangguan tidur = 0,704 dan r = -0,037); semakin besar dukungan sosial secara signifikan [5]. CRF dapat meningkatkan rasa ketergantungan kepada CRF dan kebutuhan spiritual memiliki hubungan yang orang lain sehingga beberapa pasien merasa hal ini bermakna (p=0,037; r =-0,198) dengan nilai korelasi menjadi beban untuk orang lain. Perasaan tersebut dapat kedua variabel tersebut negatif; semakin tinggi diartikan sebagai Self Perceived Burden (SPB) atau kebutuhan spiritual maka tingkat CRF penderita perasaan beban diri seseorang pasien kanker terhadap semakin rendah. Secara teknis S3C-Latent berdasarkan penelitian yang dilakukan oleh peneliti mengkombinasikan konsep stability selection [30] untuk terdahulu [35], namun tidak semua item termasuk ke menentukan struktur kausal yang stabil, Non-dominated dalam 4 faktor tersebut.
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