PEMANFAATAN PERASAN BUAH KEPEL (Stelechocarpus burahol (Blume) Hook.& Thomson) SEBAGAI ANTISEPTIK LUKA

Abstract

Fruit of kepel known contain of saponin and flavonoid, fruit of kepel is a plant that has antibacterial and antiinflamation activity. This research purposed for made juice of fruit kepel and test of open wound healing process activity. Juice of fruit kepel is made with variety of concentration, which 20%, 40%, 60%, and 80%. Negative control used aquadest and positive control used Betadine® (Povidon Iodine). This type of research is experimental research, procedure start from the preparation of test materials, first identifying plants, then make fruit juice of kepel and divide into several concentration, followed by grouping into six group of test animals. All quantitative data were statistically analyzed using Anaylsis of Variance (Anova) and continued with Tukey Test, The lowest activity on the negative control and increase on the group of juice with concentration 20%, 40%, 80%, and 60%, higher activity on the positive control. With wound healing broad parameters result that the group fruit juice of kepel concentration 60% and 80% showed the statistically analyzed was more significant (p<0.05) 178 Pharmaҫiana, Vol. 4, No. 2, 2014: 177-183 than the negative control. So it can be taken conclusion that fruit juice of kepel concentration 60% and 80% having wound healing activity.