Abstract

Starch is a carbohydrate that can be used as a binder in pharmaceutical preparations. Paracetamol has poor flowability and compactibility with its crystalline form, it is necessary to make granules by wet granulation method with starch as a binder. This study used banana peel waste (Musa paradisiaca) as a source of starch. Three granule formulations (F1, F2, and F3) were prepared using the wet granulation method with banana peel waste starch as a binder with concentrations of 5% (F1), 8% (F2), and 10% (F3) w/v. The results showed that the granule quality test included testing of moisture content, flow rate, angle of repose, and compressibility index, with the results of the granule moisture content test being 3.52%, granule flow rate 4.8 seconds, angle of repose 37.7°, and index compressibility of 10% meets the parameters of a good granule preparation.

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