Abstract

Tuberculosis is a global public health problem with 10 million people developing an active form each year. The exact incidence of the pelvic form of tuberculosis is not known due to under-reporting of asymptomatic cases, vague symptomatology and lack of reliable diagnosis. We report a case of ovarian tuberculosis mimicking cancer and peritoneal carcinosis. The case involved a 15-year-old girl, hospitalized for severe pelvic pain and secondary amenorrhea. The examination showed an altered general state, a fever, a sensitive distended abdomen. The biology showed an elevation of Ca125 to 357 IU/ml. The CT scan showed a latero-uterine mass taking contrast in a heterogeneous way with an irregular and nodular thickening of the peritoneum making evoke a peritoneal carcinosis. Exploratory laparotomy found a bilateral ovarian mass with ileo-ileal, ileo-parietal and ileo-ovarian adhesions. Biopsy of the mass and the peritoneum showed a caseo-follicular gigantocellular epitheloid granulomatosis.

Highlights

  • Tuberculosis (TB) remains a major public health problem worldwide with 10 million people developing active TB each year and 1.33 million deaths [1]

  • We report a case of ovarian tuberculosis mimicking cancer and peritoneal carcinosis

  • We report a case of ovarian tuberculosis mimicking ovarian cancer with elevated CA-125

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Summary

Introduction

Tuberculosis (TB) remains a major public health problem worldwide with 10 million people developing active TB each year and 1.33 million deaths [1]. Most (85%) TB deaths occur in developing countries, in Asia (55%) and Africa (30%), with most (75%) cases in the 15 - 45 age group [1]. 14% of reported cases of TB worldwide are extra-pulmonary [2]. The exact incidence of pelvic tuberculosis is not known due to under-reporting of asymptomatic cases, vague symptomatology and lack of reliable diagnostics [3]. We report a case of ovarian tuberculosis mimicking ovarian cancer with elevated CA-125

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