Pelvic radiation-induced sarcoma following treatment of cervical cancer

Abstract

Post-radiation sarcomas account for 0.5-5.5% of all sarcomas, and include extra skeletal osteosarcoma, fifibrosarcoma leiomyosarcoma, and malignant fifibrous histiocytoma. This article presents a case of a 53-year-old female who developed a mixed-type postradiation sarcoma three years after radiotherapy for cervical cancer. Unfortunately, the patient succumbed to the condition six months after undergoing pelvic clearance surgery. No prior relevant case reports have been identified in the literature. Consequently, we have systematically reviewed and summarized this case, conducting a comprehensive literature review to contribute valuable insights into the understanding of post-radiation sarcomas. Our objective is to underscore the importance of vigilance regarding these conditions and to provide clinicians with pertinent clinical data for informed decision-making in the realm of tumor radiotherapy.