Abstract
Aggressive pelvic angiomyxoma is a very rare mesenchymal tumor that is usually diagnosed in premenopausal female patients. The current mainly reported treatment is wide surgical excision. Other treatment options, such as radiotherapy and hormonal therapy, have been suggested as potential alternatives. A 61-year-old postmenopausal female patient presented with hematuria that led to the identification of a perirectal mass on abdominopelvic imaging. A 46-year-old female patient presented with a perineal mass of unknown etiology. Despite extensive investigations, the diagnosis could not be confirmed before surgical resection in both patients. Surgical excisions were performed and revealed the presence of an aggressive angiomyxoma with positive estrogen and progesterone tumoral receptors in both cases. Radiological and clinical recurrence was noted in one patient. Tumor regression was noted in this patient after treatment with a luteinizing hormone-releasing hormone (LHRH) agonist with long-term remission. The diagnosis of a perirectal aggressive angiomyxoma is an exceedingly rare event. Preoperative biopsy and pathological diagnosis are challenging and often yields poor results. Its slow growth and expression of hormonal receptors make noninvasive therapeutic strategies, such as radiotherapy, gonadotropin-releasing hormone agonists, or even watchful waiting, valid options in selected patients. Due to the lack of reported cases, the best treatment has yet to be elucidated.
Highlights
Aggressive pelvic angiomyxoma is a very rare mesenchymal tumor that is usually diagnosed in premenopausal female patients
A 61-year-old postmenopausal female patient presented with hematuria that led to the identification of a perirectal mass on abdominopelvic imaging
Aggressive angiomyxoma (AA) is a rare mesenchymal tumor usually found in the pelvis of young female patients [1,2]
Summary
Aggressive angiomyxoma (AA) is a rare mesenchymal tumor usually found in the pelvis of young female patients [1,2]. Pelvic magnetic resonance imaging (MRI) revealed a left perirectal mass of 10.6 x 10.7 x 4.9 cm, which was in contact with the left posterolateral vaginal wall (Figure 2). A 46-year-old healthy female patient was evaluated at our institution for a perirectal mass of unknown etiology. The patient reported the feeling of a perineal mass, similar to the one felt prior to surgery. Another MRI was performed and showed a progression of the tissular density that extended upward to a length of 10 cm. After five and eight years, respectively, a repeat MRI showed no signs of recurrence and stability of a small residual local scar (Figure 5)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
