Abstract
The paper reports the first chemical study of the porostome nudibranch Doriopsilla pelseneeri collected off the Portuguese coast (Atlantic Ocean). Two new furanosesquiterpene alcohols, pelseneeriol-1 ( 1 ) and pelseneeriol-2 ( 2 ), have been isolated together with known compounds, 15-acetoxy- ent-pallescensin-A ( 5 ), and dendocarbin-A ( 6 ), from the mantle of the nudibranch, whereas euryfuran ( 3 ) and drimane ester mixture 4 were identified in the extract of the internal glands. The structures of 1 and 2 have been determined by extensive spectroscopic studies as well as by comparison with literature model compounds. In order to assess the relative stereochemistry of 1 and 2 , full NMR assignment of related sponge metabolite microcionin-2 ( 8 ) and of co-occurring sesquiterpenes 9– 11 , that have been re-isolated from the Mediterranean sponge Fasciospongia cavernosa, has been also conducted. In particular, the relative stereochemistry of tricyclic sesquiterpene microcionin-1 ( 9 ) has now been rigorously assigned by detailed analysis of NOE difference experiments.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.