Abstract

 CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
 The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
 This review assesses pegcetacoplan (Empaveli), 54 mg/mL, solution, subcutaneous infusion.
 Indication: For the treatment of adult patients with paroxysmal nocturnal hemoglobinuria who have an inadequate response to, or are intolerant of, a C5 inhibitor.
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