Pegagan (Centella asiatica) as a functional food for health with centelloside content

Noverita Sprinse Vinolina,Riswanti Sigalingging

doi:10.1051/e3sconf/202133208008

Abstract

Pegagan or Centella asiatica is one of the wild plants that has not experienced domestication. Countries in the Eastern have been concerned about conserving medicinal plants to the sustainability of medicinal and aromatic plants. The content of secondary metabolites in Centella asiatica has been known; those are several saponin compounds, including asiaticoside, madeccasoside, and asiatic acid. This study’s goal was to determine the content of secondary metabolites of asiaticoside, madeccasoside and asiatic acid at the top (leaves and petioles) and the bottom (roots and tendrils) with a harvest age of 12 weeks after planting (WAP). The planting site was in the lowlands of Deli Serdang, in which the measuring method used the HPLC tool. According to the results, Centella asiatica, harvested at 12 WAP, had a higher content of asiaticoside and madeccasoside in the roots and tendrils than in the leaves and petioles, while the content of asiatic acid was higher in the leaves and petioles than in the roots and tendrils. The bioactive compounds contained in Pegagan (Centella asiatica) are very efficacious for various diseases. Cultivation is carried out to avoid the loss of germplasm and genetic diversity in nature so that a balance in nature can be achieved.

Highlights

Back to nature is one of the focal points in human contemporary culture development in which traditional herb plants reclaim their popularity as medicinal ingredient alternatives
This study is expected to provide information on Pegagan (Centella asiatica) cultivation techniques with appropriate harvesting methods to produce herbal ingredients with high asiaticoside, madecassoside, and asiatic acid content, which are helpful for phytopharmaca
The procedure of analysis included: 1) Pegagan (Centella asiatica) powder was used as much as 0.2 g, 2) Give 4 ml of 90% methanol (90 methanol: 10 water), 3) Place them in a shaker mixing for 5 h, 4) Filter via Whatman and mix with 1 ml of 90% methanol, 5) Filter again via filter adapter (0.45 μM), 6) Save the filtrate for HPLC test, using 20 μl for injections

Summary

Introduction

Back to nature is one of the focal points in human contemporary culture development in which traditional herb plants reclaim their popularity as medicinal ingredient alternatives. The use of Pegagan (Centella asiatica) medicinal plants is very real, while the conservation efforts are very limited so that the influence is much smaller if compared to the existing needs. The plants' response to the conditions of the growing media by harvesting at 12 WAP to the content of secondary metabolites (asiaticoside, madecassoside, and asiatic acid) in Pegagan (Centella asiatica) can be seen. The high demand for simplicia harvested from Pegagan (Centella asiatica) in nature without cultivating the plant will cause the plant to become rare or even endangered. The right time for harvesting is to obtain the optimal content of asiaticoside, madecassoside, and asiatic acid, as well as Centella asiatica biomass. This study is expected to provide information on Pegagan (Centella asiatica) cultivation techniques with appropriate harvesting methods to produce herbal ingredients with high asiaticoside, madecassoside, and asiatic acid content, which are helpful for phytopharmaca. This study is supposed to deliver information to the public and phytopharmaca managers regarding Pegagan (Centella asiatica)

Materials and Tools

Research Implementation

Results and Discussion

Conclusion