Peel bond strength of resilient liner modified by the addition of antimicrobial agents to denture base acrylic resin

Cristiane S Alcântara,Bruno C.V Gurgel,Janaina H Jorge,Karin H Neppelenbroek,Allana F.C De Macêdo,Vanessa M Urban

doi:10.1590/s1678-77572012000600004

Abstract

In order to prolong the clinical longevity of resilient denture relining materials and reduce plaque accumulation, incorporation of antimicrobial agents into these materials has been proposed. However, this addition may affect their properties.ObjectiveThis study evaluated the effect of the addition of antimicrobial agents into one soft liner (Soft Confort, Dencril) on its peel bond strength to one denture base (QC 20, Dentsply). Material and MethodsAcrylic specimens (n=9) were made (75x10x3 mm) and stored in distilled water at 37ºC for 48 h. The drug powder concentrations (nystatin 500,000U - G2; nystatin 1,000,000U - G3; miconazole 125 mg - G4; miconazole 250 mg - G5; ketoconazole 100 mg - G6; ketoconazole 200 mg - G7; chlorhexidine diacetate 5% - G8; and 10% chlorhexidine diacetate - G9) were blended with the soft liner powder before the addition of the soft liner liquid. A group (G1) without any drug incorporation was used as control. Specimens (n=9) (75x10x6 mm) were plasticized according to the manufacturers' instructions and stored in distilled water at 37ºC for 24 h. Relined specimens were then submitted to a 180-degree peel test at a crosshead speed of 10 mm/min. Data (MPa) were analyzed by analysis of variance (α=0.05) and the failure modes were visually classified. ResultsNo significant difference was found among experimental groups (p=0.148). Cohesive failure located within the resilient material was predominantly observed in all tested groups. ConclusionsPeel bond strength between the denture base and the modified soft liner was not affected by the addition of antimicrobial agents.

Highlights

The oral candidiasis known as denture stomatitis is related to the use of removable dentures and is considered the most common oral lesion observed (65%)27 in patients wearing removable dentures
Peeling away from the denture base was only observed for groups G6 and G9 (10% chlorhexidine diacetate)
The hypothesis investigated in this study that “the addition of antimicrobial agents to the resilient liner would result in alterations in the peeling bond strength to denture base resin” was rejected because there was no difference between the experimental groups assessed in comparison with the control group without the addition of drugs

Summary

Introduction

The oral candidiasis known as denture stomatitis is related to the use of removable dentures and is considered the most common oral lesion observed (65%) in patients wearing removable dentures. The etiology of denture stomatitis is multifactorial, infection by Candida spp., especially C. albicans, is considered the main etiologic factor. Different treatments for denture stomatitis are available and may include topical antifungal and systemic therapy, care with oral hygiene, denture cleaning and disinfection procedures, replacement of old dentures, elimination of anatomic irregularities, re-establishment of atraumatic occlusion, and nutritional restitution. Re-infection of the treated oral mucosa may occur in up to two weeks post-treatment, and is attributed to the survival of Candida spp. due to insufficient concentration of the antifungal agent on the denture surfaces. It is crucial to adopt methods that reduce or preferably eliminate the microorganisms from denture surfaces

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