Abstract

Typhoid fever is a life-threatening systemic infection occurring in developing countries like India. The presenting signs and symptoms of typhoid fever in children differ from adults. Some studies indicate reemergence of sensitivity of Salmonella with chloramphenicol.

Highlights

  • Typhoid fever is a life-threatening systemic infection occurring in developing countries like India

  • 73 patients were diagnosed as enteric fever and clinical features were compared among different age groups

  • Clinical profile of enteric fever in children differ with age

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Summary

Introduction

Typhoid fever is a life-threatening systemic infection occurring in developing countries like India. The presenting signs and symptoms of typhoid fever in children differ from adults. Typhoid fever is a life-threatening systemic infection occurring in developing areas of the world and continues to be a major public health problem. Over 21 million people worldwide get infected annually with estimated mortality of 2,00,000 people per year [1]. The presenting signs and symptoms of typhoid fever in children differ significantly from those in adults [2]. Salmonella typhi (S. typhi) is the causative agent which is most frequently isolated in the blood during first week of illness. In the wake of emerging multidrug resistant strains of bacteria causing typhoid fever, the disorder is known to be associated with significant morbidity and mortality. It is recognized that delay in the diagnosis and institution of appropriate therapy may significantly increase the risk of adverse outcome and mortality

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