Pediatric demyelinating disorders

Abstract

The field of pediatric-onset multiple sclerosis (MS) and other demyelinating diseases in childhood has advanced considerably since the publication of the last International Pediatric Multiple Sclerosis Study Group (IPMSSG)–sponsored Neurology ® supplement in 2007. Over the last decade, demyelinating diseases of the CNS in children, and MS in particular, have garnered considerable international focus, both in the clinical and research world but also in the lay press and public awareness. This coming of age resulted in an exponential increase in research efforts and publications, with more than 250 peer-reviewed publications on pediatric MS in the past 10 years. It has also crystallized national and international collaborations that are critical to transform the field. Contributors: IPMSSG Steering Committee Members: Maria Pia Amato: Department NEUROFARBA, Section Neurosciences, University of Florence, Italy; Brenda Banwell: The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia; Angelo Ghezzi, Divisione di Neurologia 2–Centro Studi Sclerosi Multipla, Ospedale di Gallarate, Gallarate, Italy; Rogier Q. Hintzen: Department of Neurology, MS Centre ErasMS, Neurology, Erasmus MC, Rotterdam, the Netherlands; Lauren B. Krupp: Lourie Center for Pediatric MS, Stony Brook Children's Hospital, Stony Brook University, New York; Kevin Rostasy: Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Germany; Silvia Tenembaum: Department of Neurology, National Pediatric Hospital Dr. Juan P. Garrahan. Ciudad de Buenos Aires, Argentina; Evangeline Wassmer: Department of Neurology, Birmingham Children's Hospital, UK; Emmanuelle Waubant: Pediatric MS Center, UCSF Benioff Children's Hospital, and Neurology Department, UCSF, San Francisco, CA. IPMSSG Coordinating Consultant: Jon Temme.