Pediatric cancer registry in Turkey 2002-2022: 21 years of achievement (TPOG & TPHD).

Abstract

e22004 Background: Each year 413.000 new pediatric cancer cases are expected in children and adolescents aged 0-14 globally. The access to care is still a barrier to improve the survival rates in low and middle income countries (LMICs). Pediatric cancer registry is the essential element of pediatric cancer control. Here, we present the results of the 21 years of the pediatric cancer registry from Turkey. Methods: Turkish Pediatric Oncology Group and Turkish Pediatric Hematology Association has established the pediatric cancer registry in 2002. The childhood cancer cases registered between 2002-2022 was included in this analysis. International Childhood Cancer Classification System was used for the classification. Essential demographic findings, ICD-O-3 morphology and topography codes were recorded for each case. Results: During the 21 years from 2002 to 2022, 46067 cases were registered. For all cases, median age was 6.5 year (0-19; M/F 25079/20176, 6 hermaphrodite, 6 unknown). Age distribution was 0-4 yrs, 41.5%; 5-9 yrs, 24.7%; 10-14 yrs, 23.0%; 15-19 yrs, 10.7%) The distribution of the tumor types were [number of cases, percentage of total, median age yrs, M/F]: Leukemia (13190, 28.6%, 5.6, 7640/5550); Lymphoma & other RES tumors (8194, 17.8%, 9.1, 5435/2756, 1 hermaphrodite & 2 unknown); CNS [brain & spinal] (6606, 14.3%, 6.8, 3670/2935, 1 unkown); Symphatetic system (3411, 7.4%, 2.3, 1755/1656); Retinoblastoma (1386, 3.0%, 1.5, 726/660); Renal (2095, 4.5%, 3.1, 1032/1061, 1 hermaphrodite & 1 unknown); Liver (681, 1.5%, 2.1, 400/281); Malignant bone (2809, 6.1%, 12.5, 1569/1240); Soft tissue sarcomas (3209, 7.0%, 7.3, 1810/1399); Germ cell (2663, 5.8%, 8.6, 957/1700, 4 hermaphrodite, 2 unknown); Carcinoma & other malignant epithelial (1494, 3.2%, 13.0, 721/773); Other/non-specific malignant (329, 0.7%, 7.4, 164/165). Five year survival rate was found as 70.8% Conclusions: This is a successful example of a pediatric cancer registry from a middle income country covering the period of more than 20 years. The survival rates for children and adolescents have been improved to 70% which is comparable for middle income countries and reflects the level of the pediatric cancer care in Turkey. It became a valuable source for stakeholders in national and international level.