Abstract
Lithium, is an alkali ion that is used for acute treatment and prophylaxis of mood disordes over 50 years. The most seen side effects of lithium are tremor, diarrhea, polyuria, polidipsia, hypotiroidi, weight gain, nephrogenik diabetes insipidus and nausea. Due to narrow therapeutic index, intra and interpersonal variable pharmacokinetics; close monitoring of blood lithium concentrations is recommended. Also it is suggested that lithiumneuroleptic combination can increase neurotoxicity and side effects via dopamine receptor blockade. In this case report we aimed to discuss the clinic and mechanisms of probable lithium induced pedal edema in a bipolar affective disorder patient
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