Peculiarities of the bone-marrow hemopoiesis, peripheral blood, and the elemental status of the red bone marrow of poultry resulted from copper introduction

Abstract

Metals in an electrically neutral form produced with the method of vacuum condensation from metals are finely dispersed powders. The role of chemical elements in an organism is versatile and multifunctional. However, it is necessary to pay attention to the reaction of an organism on the introduction of chemical elements with different biological roles, which is predetermined by the physiological role of organs and body systems. These include the red bone marrow, which primarily responds to endogenous and exogenous factors by its functional significance. In order to study the influence of copper nanopowders on hematopoiesis of birds, we selected 150 10-day-old broiler chickens which formed 5 groups by the method of analogs (n = 30). All said above allows us to conclude that copper nanoparticles ambiguously affect the bone-marrow hemopoiesis of poultry; increasing the dose and changing the type of introduction activate bone marrow hematopoietic function, in particular, granulocyto-, megakaryocyto-, and erythropoiesis. Different dosages and ways of introduction of copper nanoparticles, in our opinion, ambiguously affect the bone-marrow hemopoiesis of poultry when using copper in doses of 1.7 mg/kg of feed, which is 50% of the daily needs of the organism. E A Sizova et al. proved a stimulating effect of copper nanoparticles in the same dosage on liver cells of chicks.