PECULIARITIES OF SYMPTOMATIC ACQUIRED LACRIMAL OUTFLOW OBSTRUCTION IN PATIENTS WITH DIABETES MELLITUS DEPENDING ON THE DEGREE OF ITS COMPENSATION

Abstract

The aim was to identify the features of symptomatic ALOO in patients with type 2 diabetes mellitus (DM2) depending on the degree of its compensation.
 Materials and methods. The study included 56 patients with symptomatic ALOO and DM2. Patients were divided into groups according to the degree of compensation of DM2: 29 patients with decompensated DM2 (HbA1c > 7.5 %), 14 patients with subcompensated DM2 (HbA1c — 7.1–7.5 %), 13 patients with compensated DM2 (HbA1c < 7.1 %).
 In addition to standard, ophthalmic methods included measuring the size of the lacrimal punctum, the height of the lacrimal meniscus, diagnostic tests to determine tear production (Schirmer, Jones, Norn test), lacrimal, larimal suction test, and reflux test, assessment of lacrimal system balance, diagnostic lavage of lacrimal outflow system, probing of the lacrimal ducts.
 Results. Decompensated DM2 (51.8±6.7 % of patients) occurred in patients with symptomatic ALOO 2.1 and 2.2 times more often than subcompensated ((25±5.8) % of patients) and compensated DM2 ((23.2±5,7) % of patients), respectively (p<0,05). The frequency of bilateral lesions among patients with decompensated DM2 ((58.6±9.2) % of patients) was on average 1.8 times higher than in patients with subcompensated ((35.7±12.8) % of patients) and compensated DM2 ((30,8±12.8) % of patients) (p <0.05). The frequency of complete obstruction in patients with compensated DM2 ((52.9±2.1) % of the eyes) was on average 1.5 times lower than in patients with subcompensated ((79±9.3) % of the eyes) and decompensated DM2 ((78.3±6.1) % of eyes) (p<0.05). The frequency of blepharitis in decompensated DM2 ((79.3±7.5) % of patients) was on average 1.3 times higher than that in compensated ((64.3±13.3) % of patients) and subcompensated DM2 ((61.5±13.0) %) patients (p<0.05).
 Conclusions. Symptomatic ALOO is more common in patients with decompensated DM2. In patients with DM2 features of symptomatic ALOO depend on degree of compensation of DM2.