Abstract
The results of research the cytokine-secretion activity of mononuclear leukocytes, apoptosis and proliferation of lymphocytes for patients with infiltrative pulmonary tuberculosis has been presented in this article. It has been showed that patients with drug-resistant pulmonary tuberculosis had more evident of damages, particularly significant depression of proliferation of lymphocytes, decreased number of cells expressing CD95-receptor as well as disturbance the secretion of immunoregulatory cytokines.
Highlights
Представлены результаты исследования цитокинсекреторной активности мононуклеарных лейкоцитов, апоптоза и пролиферации лимфоцитов у больных инфильтративным туберкулезом легких (ТЛ)
The results of research the cytokine-secretion activity of mononuclear leukocytes, apoptosis and proliferation of lymphocytes for patients with infiltrative pulmonary tuberculosis has been presented in this article
It has been showed that patients with drugresistant pulmonary tuberculosis had more evident of damages, significant depression of proliferation of lymphocytes, decreased number of cells expressing CD95-receptor as well as disturbance the secretion of immunoregulatory cytokines
Summary
Представлены результаты исследования цитокинсекреторной активности мононуклеарных лейкоцитов, апоптоза и пролиферации лимфоцитов у больных инфильтративным туберкулезом легких (ТЛ). Целью настоящей работы явилось исследование особенностей иммунных реакций у больных туберкулезом легких в зависимости от лекарственной чувствительности M. tuberculosis. Концентрация цитокинов (пг/мл) в супернатантах культуральных суспензий мононуклеарных лейкоцитов крови у здоровых доноров и больных инфильтративным туберкулезом легких (Ме (Q1—Q3) IL-4 Базальная При инкубации с вакцинным штаммом BCG
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