Abstract

Summary. The prevalence of myocardial infarction and its leading role in the structure of overall and cardiovascular mortality encourages the search for predictors of complicated course of disease and the search for optimal means to prevent adverse events. The aim of the study – to establish features of cardiac arrhythmias in patients with myocardial infarction without ST-segment elevation depending on the degree of coronary artery lesions. Materials and Methods. The study involved 156 patients with NSTEMI aged 38 to 80 years. All patients were examined according to the current treatment protocol for patients with acute coronary syndrome without ST segment elevation and daily Holter ECG monitoring was performed for 3-5 days after hospitalization. Results. It was found that the degree of coronary artery lesions is positively correlated with the likelihood of severe adverse ventricular arrhythmias and episodes of silent myocardial ischemia in the early period. Conclusions. By determining the total score of coronary artery disease, it is possible to stratify the adverse course of NSTEMI, in particular, the occurrence of fatal ventricular arrhythmias in the early period.

Highlights

  • Myocardial infarction (MI) is one of the leading causes of death and disability worldwide

  • It was found that the degree of coronary artery lesions is positively correlated with the likelihood of severe adverse ventricular arrhythmias and episodes of silent myocardial ischemia in the early period

  • By determining the total score of coronary artery disease, it is possible to stratify the adverse course of NSTEMI, in particular, the occurrence of fatal ventricular arrhythmias in the early period

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Summary

Introduction

Myocardial infarction (MI) is one of the leading causes of death and disability worldwide. In Ukraine, the frequency of registration of MI per capita is the highest in the European population, which puts this problem in the category of priority medical and social problems for our society [1]. In the last 20 years, there has been a trend of increasing incidence of myocardial infarction without. ST-segment elevation (NSTEMI), which, according to some data, accounts for about half of all registered MI [2, 3]. The main problem with NSTEMI is that the long-term prognosis of these patients remains unsatisfactory, and mortality one year after the disaster equals or even exceeds that of STEMI [4]. Of great scientific interest are studies that develop the concept of predicting the nature of coronary artery disease using clinical and various non-invasive

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