Abstract
The frequency of cholelithiasis, including in children, is constantly growing. For the moment there is no treatment algorithm of this disease after cholecystectomy, which determines the urgency of this problem. The article presents the pathogenetic justification of substitution therapy with enzyme drugs, sparing therapy with antacids, hepatoprotectors and cholespasmolytics, as well as probiotics in the early postoperative period in children with cholelithiasis who underwent cholecystectomy. There are data proving fallacy of prescribing ursodeoxycholic acid during this period. Particular attention is paid to the mechanism of action of drugs and the possibility of their use for the prevention and / or treatment of postcholecystectomy syndrome in children of different age groups. We describe our personal experience in the use of drugs in children with cholelithiasis, who underwent cholecystectomy.
Highlights
The frequency of cholelithiasis, including in children, is constantly growing
For the moment there is no treatment algorithm of this disease after cholecystectomy, which determines the urgency of this problem
The article presents the pathogenetic justification of substitution therapy with enzyme drugs, sparing therapy with antacids, hepatoprotectors and cholespasmolytics, as well as probiotics in the early postoperative period in children with cholelithiasis who underwent cholecystectomy
Summary
Особенности консервативного лечения детей с желчнокаменной болезнью после холецистэктомии. Peculiarities of Conservative Treatment of Children with Cholelithiasis after Cholecystectomy. В статье дано патогенетическое обоснование необходимости проведения заместительной терапии ферментными препаратами, назначения щадящей терапии антацидами, гепатопротекторами и холеспазмолитиками, а также подбора пробиотиков в ранний постоперационный период у детей с желчнокаменной болезнью, перенесших холецистэктомию. Особое внимание уделено механизму действия лекарственных средств и возможности их использования для профилактики и/или лечения постхолецистэктомического синдрома у детей разных возрастных групп. Представлен личный опыт применения лекарственных средств у детей с желчнокаменной болезнью, перенесших холецистэктомию. The article presents the pathogenetic justification of substitution therapy with enzyme drugs, sparing therapy with antacids, hepatoprotectors and cholespasmolytics, as well as probiotics in the early postoperative period in children with cholelithiasis who underwent cholecystectomy. For citation: Yakimova L.V., Kharitonova L.A. Peculiarities of Conservative Treatment of Children with Cholelithiasis after Cholecystectomy.
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