Abstract
Ulcerative colitis (UC) is a chronic inflammatory and recurrent disorder that is characterized by bowel inflammation. Among the extraintestinal manifestations (EIMs) that associate UC are the joints and renal manifestations. Joint affection in the form of arthritis can precede the intestinal manifestations of UC. However, renal affection with amyloidosis does not precede the UC diagnosis. Herein, we report a case of 26-year-old male diagnosed with UC after having peripheral arthritis for long time in addition to spondylitis and kidney amyloidosis.
Highlights
Ulcerative colitis (UC) is one of two types of inflammatory bowel disease (IBD)
Review of literature reveals that Extraintestinal manifestations (EIMs) can be seen in 25–40% of IBD patients [4]
Arthritis related to IBD is considered a subset of the seronegative spondyloarthropathies
Summary
Ulcerative colitis (UC) is one of two types of inflammatory bowel disease (IBD). Its main presentation is episodic periods of a variety of symptoms such as abdominal pain, bleeding per rectum, and diarrhea along with periods of remission [1]. Medical treatment of UC differs according to the severity and extent of the disease and includes 5-aminosalicylates, corticosteroids, immunosuppressants, and anti-TNF alpha agents [2, 3]. Extraintestinal manifestations (EIMs) are seen in 25–40% of UC patients [4]. As a part of EIM, can affect the axial, peripheral joints, or a combination of both [5]. UC is an uncommon cause of secondary amyloidosis; it can have different renal presentations ranging from asymptomatic proteinuria to nephrotic syndrome [6]
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