Abstract
1,1′-Polymethylenebis(2-alkyl-sn-glycero-3-phosphocholine (L-20: -(CH2)20- and C10H21-; L-32: -(CH2)32- and C16H33- for the polymethylene and alkyl residues, respectively) were synthesized. Upon sonication, L-20 furnished sausage-like liposomes with a membrane of about 41Åthickness. The liposomes underwent gel-to-liquid crystalline phase transition at 7°C (Tm) with an enthalpy (ΔH) of 2–3 kcal/mol. L-32, on the other hand, gave rise to planar membranes of about 56 Å thickness with a Tm of 61°C and a ΔH of 16.5 kcal/mol. The diglycerophospholipids were also brought into Langmuir-Blodgett (LB) membranes by means of a film balance, displaying peculiar surface pressure-surface area isotherms. It was concluded from these results that L-20 and L-32 took an extended form in an aqueous environment to form monomolecular layers while they were bent into a U form in the water/air interface to produce the LB monolayer.
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