Pecularities of Arterial Hypertension Prevalence and Intervisit Variability of Blood Pressure in Khmelnytskyi Region

Abstract

The objective: to carry out the comparative analysis of arterial hypertension (AH) prevalence in rural and city population of Khmelnytskyi region, and to establish the frequency of patients with high intervisit variability of blood pressure (IVBP) in rural population.Materials and methods. We carried out the analysis of prevalence of AH and its major complications (myocardial infarction and cerebrovascular accident) in rural and city population of Khmelnytskyi region in dynamics during the period 2016–2018, based on official statistical data (form 12). The IVBP was studied in a random sample of 160 rural males with uncomplicated AH. Systolic blood pressure (BP), diastolic BP and the pulse BP were measured at each visit to doctor. IVBP was assessed by the standard deviation (SD) value, calculated from the BP recordings at the four visits to doctor. We also calculated the variation coefficient as a SD/average BP ratio.Results. It was established that the prevalence of AH in the population of Khmelnytskyi region was high (39 352,5 per 100 000 inhabitants), accompanied by the higher prevalence of stroke, in comparison with average stroke prevalence inUkraine. The prevalence of AH in rural population exceeded the corresponding index in the urban population, and was characterized by considerable variations in certain rural areas. The frequency of high IVBP in rural AH males was 51,25%. The high IVBP among males was mainly caused by significant variation of systolic BP (50,62%), and high variability of diastolic BP was observed only among 12,5% of patients with AH. The lipid profile changes and hypertension-mediated organ damage (namely heart and kidneys) were more pronounced in patients with high IVBP, as compared to males with low IVBP.Conclusions. The prevalence of AH in the population of Khmelnytskyi region is high, with the higher value in rural population as compared to the city one. The prevalence of stroke in Khmelnytskyi region remains high, with the tendency to increase during the last several years. Such unfavorable dynamics could be at least partially related to the high frequency (more than 50%) of patients with AH and high IVBP.