Abstract
Workplace exposure to Trimellitic Anhydride (TMA) can elicit specific IgG and IgE antibody responses leading to occupational asthma (OA). An immuno-surveillance program to identify and remove workers with TMA-specific serum IgE, who are at risk for OA, has been previously developed. This purpose of this study was to determine whether the kinetics of specific antibody responses can differentiate workers who only develop TMA specific IgG from those that progress to specific IgE.
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